Currently content structure remembers opened paths, and you have to close the nodes you have opened.
On large sites that can be a bit of a hassle , as you open paths to look for something and when your done you have lots of open paths that are open when you come back.

Proposed contentstructuremenu.ini setting:

[TreeMenu]
# Use cookies to remember opened paths and keep then
# open until closed by user.
# If disabled only current path will be opened automatically.
MenuPersistence=enabled